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biogen fda approvalpimavanserin fda approvalatezolizumab fda approvalribociclib fda approvaldupilumab fda approvaldurvalumab fda approvalfda approved immunotherapyibrutinib fda approvalbinimetinib fda approvalmolnupiravir fda approvalacalabrutinib fda approvalxpovio fda approval